G-POEM: non-invasive pyloroplasty

by Jim Sliney Jr For patients whose primary symptoms of gastroparesis are nausea and vomiting, and in whom other gastric procedures have failed, there is a hopeful procedure and a related study going on. G-POEM stands for Gastric per-oral Endoscopic Myotomy, which is a procedure using endoscopy (a camera attached to a tube that, in … Continue reading G-POEM: non-invasive pyloroplasty

Effect of Endoscopic Pyloric Therapies for Patients with Nausea and Vomiting and Functional Obstructive Gastroparesis

Here is an article from the Autonomic Neuroscience: Basic and Clinical Journal. "Conclusion: Pyloric therapies appear to be effective treatments in symptomatic patients with GP and 3 cpm GMA and controlled trials are warranted." Wellington, J., et al., Effect of endoscopic pyloric therapies for patients with nausea and vomiting and functional obstructive gastroparesis, Auton. Neurosci. (2016), http://dx.doi.org/10.1016/j.autneu.2016.07.004Continue reading Effect of Endoscopic Pyloric Therapies for Patients with Nausea and Vomiting and Functional Obstructive Gastroparesis

Relamorelin is found to accelerate gastric emptying & reduce vomiting (Study)

Remalorelin was found, in a randomized double-blind, placebo-controlled study, to reduce the frequency and intensity of vomiting, and to accelerate gastric emptying in adult patients with diabetic Gastroparesis.  You can find the original article here on EndocinologyAdisor.com You can see the published study results here in  Gastrojournal.org Relamorelin is under development by Rhythm Pharmaceuticals.  JIm Sliney Jr, Editor, ThePactBlog

Final Report to the FDA

Patient Powered Drug Development: Platform For Engaging Everyone Responsibly Gastroparesis-Patient Association for Cures and Treatments (G-PACT) Advocacy Organization Engagement September 9, 2015 For Delivery To: The Food and Drug Administration (FDA) Prepared By: Cyan James, Genetic Alliance Sharon F. Terry, Genetic Alliance Rex Edwards Jim Sliney Jr., G-PACT Contact: Genetic Alliance 4301 Connecticut Ave NW … Continue reading Final Report to the FDA